Therapeutics & Vaccines
USE OF TOLL-LIKE RECEPTOR 4 AGONISTS TO TREAT INFLAMMATION AND TISSUE INJURY
WARF: P200327US02
Inventors: Peiman Hematti, John Kink, Christian Capitini, Matthew Forsberg, Reinier Hernandez, Zachary Rosenkrans, Nicholas Hess
The Invention
The disclosure relates to populations of educated macrophages and monocytes generated ex vivo or in vivo, and methods of making and using the same using lipid A aminoalkyl glucosaminide phosphate molecules, such as CRX molecules or extracellular vesicles (EVs) from mesenchymal stromal cells (MSC) stimulated with CRX molecules. Also described are EVs and methods for making and using the same from MSCs exposed to CRX.
Additional Information
For More Information About the Inventors
Tech Fields
For current licensing status, please contact Andy DeTienne at [javascript protected email address] or 608-960-9857