WARF Advances in Engineering and Computer Science

Therapeutics & Vaccines

COVID-19 Vaccine

View U.S. Patent Application Publication No. US-2021-0300970 in PDF format.

WARF: P200268US03

Inventors: Joseph Barbieri, Eric Johnson, Sabine Pellett, William Tepp, Amanda Przedpelski

The Invention

Provided herein are antigenic peptides comprising the SARS-CoV-2 spike protein receptor binding domain (CRBD) polypeptide or portions thereof, linked to a non-catalytic, nontoxic tetanus toxin variant (i.e., a modified tetanus toxin or "MTT") and vaccine compositions comprising the same. In addition, provided herein are methods for making and using CRBDMTT fusion proteins as immunogenic agents.

Additional Information

For More Information About the Inventors

Eric Johnson

Tech Fields

Therapeutics & Vaccines : Vaccines

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