Wisconsin Alumni Research Foundation

WARF Therapeutics Symposium

Chemistry Building, North Tower, Room S413 1101 University Ave., Madison, WI

Join WARF Therapeutics, the UW-Madison Department of Chemistry and the UW-Madison Synthesis and Catalysis Center for the 2023 WARF Therapeutics Symposium. 3:30-4:15 p.m. Student Presentations Ben Chi, Weix Group Environmentally Friendly Nickel-Catalyzed Reductive Difluoromethylation of Aryl Bromides Emily Schroeder, Schomaker Group Expanding the Scope of Silver-BOX Catalyzed Enantioselective C-H Amination via Nitrene Transfer Tony Meza,…

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Phenylketonuria: Insights into Pathophysiology and Novel Therapeutics

John D. Wiley Conference Center, Waisman Center 1500 Highland Ave., Madison, WI

Phenylketonuria (PKU), due to recessively inherited phenylalanine hydroxylase (PAH) deficiency, is among the most common inborn errors of metabolism with an incidence of 1:16,000 live births in the US. PAH deficiency causes accumulation of the amino acid phenylalanine (Phe) to extremely high concentrations throughout the body but most importantly in brain. The precise molecular mechanisms…

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